Symbol
Name
ID

Traf3ip2
TRAF3 interacting protein 2
MGI:2143599

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Increased circulating IgE level	Cutaneous anergy	Abnormality of blood and blood-forming tissues	Hypereosinophilia	Abnormal B cell count	Abnormal proportion of CD4-positive T cells	Abnormal proportion of CD8-positive T cells	Abnormal natural killer cell count
Disease(s) Associated with TRAF3IP2
chronic mucocutaneous candidiasis

Mouse Phenotypes

impaired macrophage chemotaxis

enlarged spleen

increased spleen weight

spleen hyperplasia

increased immature B cell number

increased transitional stage B cell number

abnormal transitional stage B cell morphology

increased dendritic cell number

increased follicular B cell number

increased marginal zone B cell number

increased B cell number

abnormal spleen B cell corona morphology

impaired eosinophil recruitment

impaired neutrophil recruitment

increased IgE level

increased IgG1 level

increased IgG2c level

increased IgG level

increased immunoglobulin level

Availability

Mouse Genotype

Traf3ip2^adjm/Traf3ip2^adjm

Traf3ip2^tm1.1Lix/Traf3ip2^tm1.1Lix

Traf3ip2^tm1Sbn/Traf3ip2^tm1Sbn

Traf3ip2^tm1Lix/Traf3ip2^tm1.1Lix
Tg(CD19-cre/ERT2)1Cgn/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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